Synovial remodelling and vascularization by Dickkopf-1 in osteoarthritis
نویسندگان
چکیده
منابع مشابه
Dickkopf-1 (Dkk-1) in plasma and synovial fluid is inversely correlated with radiographic severity of knee osteoarthritis patients
BACKGROUND Osteoarthritis (OA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Dickkopf-1 (Dkk-1) is a critical mediator of osteoblastogenesis and regulates the joint remodeling. The aim of this study was to examine plasma and synovial fluid Dkk-1 levels of patients with primary knee OA and to investigate their relationship wit...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2012
ISSN: 1759-4790,1759-4804
DOI: 10.1038/nrrheum.2012.116